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KMID : 0614619940260020363
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Korean Journal of Gastroenterology
1994 Volume.26 No. 2 p.363 ~ p.368
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A Case of Peutz-Jeghers Syndrome with Malignant Change and hepatic Metastasis
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서보정
이복근/박양훈/권기호/김영묵/이충원/이동윤/이준상/백옥지
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Abstract
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The Peutz-Jeghers syndrome, characterized by pigmentation of the skin and mucous membranes and gastrointestinal polyposis of harmatomatous variety, has been well documented, there have been conflicting view, however, as to frequency with which
malignant
change occurs in the poly. There are insufficient data to establish this syndrome as a precancerous condition but documented cases of gastrointestinal cancer arising in this syndrome have been reported with an incidence of 2-3%. This report is
concerned
with our experience with case of Peutz-Jeghers syndrome with adenocarcinoma as arising in colonic polyps, which metastasized to omentum and regional lymph nodes and liver Histologically the polyps were mostly harmatomatous and one was transformed
into
adenocarcinoma and liver showsed adenocarcinoma in the metastatic sites.(Korea J Gastroenterol 1994 ; 26 : 363-368)
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KEYWORD
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